Invention Grant
- Patent Title: CGRP receptor antagonists
- Patent Title (中): CGRP受体拮抗剂
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Application No.: US11664905Application Date: 2005-10-05
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Publication No.: US07659264B2Publication Date: 2010-02-09
- Inventor: Christopher S. Burgey , James Z. Deng , Craig Potteiger , Theresa M. Williams
- Applicant: Christopher S. Burgey , James Z. Deng , Craig Potteiger , Theresa M. Williams
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent William Krovatin; John C. Todaro
- International Application: PCT/US2005/035654 WO 20051005
- International Announcement: WO2006/041830 WO 20050420
- Main IPC: C07D403/12
- IPC: C07D403/12 ; C07D403/14 ; A61K31/55
Abstract:
The present invention is directed to compounds of Formula I: Formula I: I and Formula II: (where variables R1, R2, R3, R4, A, B, J, Q, T, V, W, X and Y are as defined herein) useful as antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as headache, migraine and cluster headache. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
Public/Granted literature
- US20080070899A1 Cgrp Receptor Antagonists Public/Granted day:2008-03-20
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