Invention Grant
US07659267B2 1,3-Benzothiazinone derivatives, process for producing the same use thereof
失效
1,3-苯并噻嗪酮衍生物，其制备方法相同
- Patent Title: 1,3-Benzothiazinone derivatives, process for producing the same use thereof
- Patent Title (中): 1,3-苯并噻嗪酮衍生物，其制备方法相同
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Application No.: US10537520Application Date: 2003-12-04
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Publication No.: US07659267B2Publication Date: 2010-02-09
- Inventor: Masahiro Kajino , Yutaka Nakayama , Haruhide Kimura
- Applicant: Masahiro Kajino , Yutaka Nakayama , Haruhide Kimura
- Applicant Address: JP Osaka-Shi
- Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee Address: JP Osaka-Shi
- Agency: Edwards Angell Palmer & Dodge LLP
- Agent David G. Conlin; Dwight D. Kim
- Priority: JP2002-353546 20021205
- International Application: PCT/JP03/15535 WO 20031204
- International Announcement: WO2004/060881 WO 20040722
- Main IPC: C07D279/16
- IPC: C07D279/16 ; A61K31/5415
Abstract:
As prophylactic and/or therapeutic agents for cardiovascular diseases, bone or joint diseases, infectious diseases, inflammatory diseases, kidney diseases, etc. having safe and excellent effects of cell death inhibition, MIF binding, etc., there are provided compounds represented by formula: [wherein, R1 represents a halogen atom, etc., R2 represents a group represented by formula: (wherein, R3 represents hydrogen atom, an optionally substituted alkoxy, etc., R4 represents hydrogen atom, bromine atom, cyano, etc., R5 represents hydrogen atom, hydroxy, etc., R6 represents hydrogen atom, etc., R7 represents hydrogen atom, etc.) etc., and n represents an integer of 0 to 4] or salts thereof.
Public/Granted literature
- US20060052371A1 1,3-Benzothiazinone derivatives, process for producing the same and use thereof Public/Granted day:2006-03-09
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