Invention Grant
- Patent Title: Modulators of ATP-binding cassette transporters
- Patent Title (中): ATP结合盒转运蛋白的调节剂
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Application No.: US11804726Application Date: 2007-05-18
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Publication No.: US07659268B2Publication Date: 2010-02-09
- Inventor: Sara Hadida-Ruah , Matthew Hamilton , Mark Miller , Peter D. J. Grootenhuis , Brian Bear , Jason McCartney , Jinglan Zhou , Frederick van Goor
- Applicant: Sara Hadida-Ruah , Matthew Hamilton , Mark Miller , Peter D. J. Grootenhuis , Brian Bear , Jason McCartney , Jinglan Zhou , Frederick van Goor
- Applicant Address: US MA Cambridge
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Cambridge
- Agent Michael J. DiVerdi
- Main IPC: A61K31/5377
- IPC: A61K31/5377 ; A61K31/497 ; A61K31/506 ; A61K31/4418 ; A61K31/443 ; C07D413/00 ; C07D401/00 ; C07D213/02 ; C07D405/00
Abstract:
Compounds of the present invention, and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.
Public/Granted literature
- US20080019915A1 Modulators of ATP-binding cassette transporters Public/Granted day:2008-01-24
Information query
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