Invention Grant
- Patent Title: Pyrimidine compound having dibenzylamine structure and medicament comprising the same
- Patent Title (中): 具有二苄胺结构的嘧啶化合物和包含其的药物
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Application No.: US12100831Application Date: 2008-04-10
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Publication No.: US07659271B2Publication Date: 2010-02-09
- Inventor: Tadaaki Ohgiya , Toru Miura , Ayumu Okuda , Toshiharu Arai , Koichi Yamazaki , Taro Aoki , Katsutoshi Miyosawa , Haruki Shibata , Kimiyuki Shibuya
- Applicant: Tadaaki Ohgiya , Toru Miura , Ayumu Okuda , Toshiharu Arai , Koichi Yamazaki , Taro Aoki , Katsutoshi Miyosawa , Haruki Shibata , Kimiyuki Shibuya
- Applicant Address: JP Aichi
- Assignee: Kowa Company, Ltd.
- Current Assignee: Kowa Company, Ltd.
- Current Assignee Address: JP Aichi
- Agency: Greenblum & Bernstein, P.L.C.
- Main IPC: C07D239/42
- IPC: C07D239/42 ; A61K31/505
Abstract:
A compound represented by the following general formula (I), wherein R1, R2, R3, R4 and R5 represent hydrogen atom, a halo(lower alkyl) group, cyano group and the like, R6 represents an alkyl group, a cycloalkyl group and the like, R7, R8, R9 and R10 represent hydrogen atom, a halogen atom, a lower alkyl group, a halo(lower alkyl) group and the like, R11 and R12 represent hydrogen atom, a lower alkyl group, a (lower cycloalkyl) (lower alkyl) group and the like, and R13 represents hydrogen atom, a halogen atom, a lower alkoxy group and the like, which has potent inhibitory activity on cholesterol ester transfer protein (CETP).
Public/Granted literature
- US20090082352A1 NOVEL PYRIMIDINE COMPOUND HAVING DIBENZYLAMINE STRUCTURE AND MEDICAMENT COMPRISING THE SAME Public/Granted day:2009-03-26
Information query
