Invention Grant
- Patent Title: CCR9 inhibitors and methods of use thereof
- Patent Title (中): CCR9抑制剂及其使用方法
-
Application No.: US11974850Application Date: 2007-10-16
-
Publication No.: US07659272B2Publication Date: 2010-02-09
- Inventor: Paul Fleming , Geraldine C. B. Harriman , Zhan Shi , Chen Shaowu
- Applicant: Paul Fleming , Geraldine C. B. Harriman , Zhan Shi , Chen Shaowu
- Applicant Address: US MA Cambridge
- Assignee: Millennium Pharmaceuticals, Inc.
- Current Assignee: Millennium Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Main IPC: C07D401/12
- IPC: C07D401/12 ; C07D401/14 ; C07D403/12 ; C07D403/14 ; A61K31/4427 ; A61K31/497 ; A61K31/506 ; A61P19/02 ; A61P29/00 ; A61P1/00
Abstract:
The invention relates to compounds represented by Structural Formula I, which can bind to CCR9 receptors and block the binding of a ligand (e.g., TECK) to the receptors. The invention also relates to a method of inhibiting a function of CCR9, and to the use compounds represented by Structural Formula I in research, therapeutic, prophylactic and diagnostic methods.
Public/Granted literature
- US20080103180A1 CCR9 inhibitors and methods of use thereof Public/Granted day:2008-05-01
Information query
