Invention Grant
US07659317B2 Methods to prepare carbon-isotope labeled organohalides with high specific radioactivity from carbon-isotope monoxide
失效
从碳同位素一氧化碳制备具有高比放射性的碳同位素标记的有机卤化物的方法
- Patent Title: Methods to prepare carbon-isotope labeled organohalides with high specific radioactivity from carbon-isotope monoxide
- Patent Title (中): 从碳同位素一氧化碳制备具有高比放射性的碳同位素标记的有机卤化物的方法
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Application No.: US10592555Application Date: 2005-03-10
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Publication No.: US07659317B2Publication Date: 2010-02-09
- Inventor: Jonas Eriksson , Bengt Langstrom , Gunnar Antoni
- Applicant: Jonas Eriksson , Bengt Langstrom , Gunnar Antoni
- Applicant Address: GB Buckinghamshire
- Assignee: GE Healthcare Limited
- Current Assignee: GE Healthcare Limited
- Current Assignee Address: GB Buckinghamshire
- Agent Craig Bohlken
- International Application: PCT/IB2005/000601 WO 20050310
- International Announcement: WO2005/090267 WO 20050929
- Main IPC: C07C319/02
- IPC: C07C319/02 ; C07C17/00 ; C07C27/06
Abstract:
Methods and reagents for labeling synthesis of organohalides by transition metal mediated carbonylation reactions using carbon-isotope labeled carbon monoxide are provided. The resultant carbon-isotope labeled organohalides are useful as radiopharmaceuticals, especially for use as precursors in Positron Emission Tomography (PET). Associated PET tracers and kits for PET studies are also provided.
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