Invention Grant
US07659384B2 Polynucleotides encoding fully human antibodies against human 4-1BB
有权
针对人4-1BB编码完全人抗体的多核苷酸
- Patent Title: Polynucleotides encoding fully human antibodies against human 4-1BB
- Patent Title (中): 针对人4-1BB编码完全人抗体的多核苷酸
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Application No.: US11903106Application Date: 2007-09-20
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Publication No.: US07659384B2Publication Date: 2010-02-09
- Inventor: Maria Jure-Kunkel , Laura J. Hefta , Marc Santoro , Subinay Ganguly , Edward L. Halk
- Applicant: Maria Jure-Kunkel , Laura J. Hefta , Marc Santoro , Subinay Ganguly , Edward L. Halk
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Paul D. Golian
- Main IPC: C07H21/00
- IPC: C07H21/00 ; C12N5/16 ; C12N15/63 ; C12P21/02
Abstract:
Fully human antibodies and antigen-binding portions thereof that bind to human 4-1BB and that allow binding of human 4-1BB to a human 4-1BB ligand. In one aspect, the antibody is an IgG4 antibody. Also provided is a method for treating a disease in a subject comprising administering a therapeutically effective amount of the antibody to said subject.
Public/Granted literature
- US20090068192A1 Fully human antibodies against human 4-1BB Public/Granted day:2009-03-12
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