Invention Grant
US07659426B2 Target protein of anticancer agent and novel anticancer agent (spnal) corresponding thereto
失效
抗癌剂的靶蛋白和与其对应的新型抗癌剂（spnal）
- Patent Title: Target protein of anticancer agent and novel anticancer agent (spnal) corresponding thereto
- Patent Title (中): 抗癌剂的靶蛋白和与其对应的新型抗癌剂（spnal）
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Application No.: US10573166Application Date: 2004-11-30
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Publication No.: US07659426B2Publication Date: 2010-02-09
- Inventor: Akito Tanaka , Akira Yamazaki , Takeshi Tsutsumi , Tomohiro Terada , Masayuki Haramura
- Applicant: Akito Tanaka , Akira Yamazaki , Takeshi Tsutsumi , Tomohiro Terada , Masayuki Haramura
- Applicant Address: JP
- Assignee: Reverse Proteomics Research Institute Co., Ltd.
- Current Assignee: Reverse Proteomics Research Institute Co., Ltd.
- Current Assignee Address: JP
- Agency: Barnes & Thornburg LLP
- Agent Sandil K. Devadas
- Priority: JP2003-401132 20031201
- International Application: PCT/JP2004/018108 WO 20041130
- International Announcement: WO2005/054181 WO 20050616
- Main IPC: A01N41/10
- IPC: A01N41/10
Abstract:
The present invention provides a pharmaceutical composition containing, as an active ingredient, a compound that specifically binds to KSRP or a functional fragment thereof, and a screening method for the compound. KSRP is a novel target protein for anticancer agents; a compound capable of regulating the expression and activity of such a protein and a pharmaceutical composition containing it are highly useful for proliferative diseases, particularly as anticancer agents. By providing the novel target protein, the mechanism behind the anticancer effect that has conventionally been unexplainable can be elucidated.
Public/Granted literature
- US20070082955A1 Novel target protein of anticancer agent and novel anticancer agent (spnal) corresponding thereto Public/Granted day:2007-04-12
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