Invention Grant
- Patent Title: Method for making homozygous genetic modifications
- Patent Title (中): 纯合遗传修饰方法
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Application No.: US11904558Application Date: 2007-09-27
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Publication No.: US07659442B2Publication Date: 2010-02-09
- Inventor: William Poueymirou , Thomas M. DeChiara , Wojtek Auerbach , David Frendewey , David M. Valenzuela
- Applicant: William Poueymirou , Thomas M. DeChiara , Wojtek Auerbach , David Frendewey , David M. Valenzuela
- Applicant Address: US NY Tarrytown
- Assignee: Regeneron Pharmaceuticals, Inc.
- Current Assignee: Regeneron Pharmaceuticals, Inc.
- Current Assignee Address: US NY Tarrytown
- Agent Tor Smeland, Esq.; Ying-Zi Yang; Valeta Gregg, Esq.
- Main IPC: C12N16/00
- IPC: C12N16/00
Abstract:
Methods of generating modified embryos and mammals by introduction of donor cells into an early stage embryo are provided, such that the resulting embryo and animal generated therefrom has a significant contribution to all tissues from the donor cells and is capable of transmitting the donor cell DNA.
Public/Granted literature
- US20080078001A1 Method for making homozygous genetic modifications Public/Granted day:2008-03-27
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