Methods and apparatus are configured to provide data to generate and/or render (medical) images using medical volumetric data sets by electronically analyzing a medical volume data set associated with a patient that is automatically electronically divided into a plurality of local histograms having intensity value ranges associated therewith and programmatically generating at least one α-histogram of data from the local histograms used for at least one of peak detection, transfer function design or adaptation, tissue detection or tissue classification.