An integrated multi-function sensor system has a head having a slot to accept a tube of a deformable material and a plurality of sensor elements mounted in the walls of the head slot to confront a tube in the slot, each sensor element being for affecting sensing of a condition relating to a liquid in the tube. An integrated electronic circuit including a microprocessor operates to determine the various conditions of a liquid flowing in the tube sensed by the sensor elements, which conditions include detection of air bubbles and/or particles by ultrasonic sensing elements, detection of an occlusion in the liquid flow by sensing the deformation of the tube wall by a force sensing element, determining the temperature of the liquid by an infrared temperature sensing element, and determining the color of the liquid by optical elements.