Invention Grant
US07662178B2 C3 exoenzyme-coated stents and uses thereof for treating and preventing restenosis
失效
C3外切酶支架及其用于治疗和预防再狭窄的用途
- Patent Title: C3 exoenzyme-coated stents and uses thereof for treating and preventing restenosis
- Patent Title (中): C3外切酶支架及其用于治疗和预防再狭窄的用途
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Application No.: US12150695Application Date: 2008-04-29
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Publication No.: US07662178B2Publication Date: 2010-02-16
- Inventor: Steven O. Marx , Andrew R. Marks
- Applicant: Steven O. Marx , Andrew R. Marks
- Applicant Address: US NY New York
- Assignee: The Trustees of Columbia University in the City of New York
- Current Assignee: The Trustees of Columbia University in the City of New York
- Current Assignee Address: US NY New York
- Agency: Cooper & Dunham LLP
- Agent John P. White
- Main IPC: A61F2/82
- IPC: A61F2/82 ; A61F2/00

Abstract:
This invention provides a stent for implantation in a blood vessel or other tissue, wherein the stent is coated with or contains C3 exoenzyme, a chimeric version thereof or an inhibitor of RhoA. This invention also provides a method for treating or inhibiting the onset of restenosis in a subject which comprises implanting one of the instant stents in the subject's blood vessel.
Public/Granted literature
- US20080208326A1 C3 exoenzyme-coated stents and uses thereof for treating and preventing restenosis Public/Granted day:2008-08-28
Information query
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