Invention Grant
US07662367B2 Pharmaceutical compositions for the treatment of TNF-α related disorders
有权
用于治疗TNF-α相关疾病的药物组合物
- Patent Title: Pharmaceutical compositions for the treatment of TNF-α related disorders
- Patent Title (中): 用于治疗TNF-α相关疾病的药物组合物
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Application No.: US11472864Application Date: 2006-06-22
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Publication No.: US07662367B2Publication Date: 2010-02-16
- Inventor: John R. Desjarlais , Paul Michael Steed , Jonathan Zalevsky , David Edmund Szymkowski , David F. Carmichael
- Applicant: John R. Desjarlais , Paul Michael Steed , Jonathan Zalevsky , David Edmund Szymkowski , David F. Carmichael
- Applicant Address: US CA Monrovia
- Assignee: Xencor, Inc.
- Current Assignee: Xencor, Inc.
- Current Assignee Address: US CA Monrovia
- Agency: Morgan Lewis & Bockius LLP
- Agent Robin M. Silva, Esq.; David C. Foster, Esq.
- Main IPC: A61K38/19
- IPC: A61K38/19 ; A61K38/00 ; C07K38/00
Abstract:
The invention relates to a pharmaceutical composition comprising a variant TNF-α protein that inhibits the activity of soluble TNF-α while substantially maintaining the activity of transmembrane TNF-α a buffer and a tonicity agent wherein said composition has a pH from approximately 5.0 to 8.0.
Public/Granted literature
- US20080187509A1 Pharmaceutical compositions for the treatment of TNF-alpha related disorders Public/Granted day:2008-08-07
Information query
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