Invention Grant
US07662375B2 Use of glucose-6-phosphate isomerase and antibodies thereto for the diagnosis and therapy of arthritis, and test of anti-arthritic compounds
有权
使用葡萄糖-6-磷酸异构酶及其抗体进行关节炎的诊断和治疗，并测定抗关节炎化合物
- Patent Title: Use of glucose-6-phosphate isomerase and antibodies thereto for the diagnosis and therapy of arthritis, and test of anti-arthritic compounds
- Patent Title (中): 使用葡萄糖-6-磷酸异构酶及其抗体进行关节炎的诊断和治疗，并测定抗关节炎化合物
-
Application No.: US11360515Application Date: 2006-02-24
-
Publication No.: US07662375B2Publication Date: 2010-02-16
- Inventor: Christophe Benoist , Isao Matsumoto , Anne-Sophie Korganow , Diane Mathis , Mariana Maccioni , Hong Ji
- Applicant: Christophe Benoist , Isao Matsumoto , Anne-Sophie Korganow , Diane Mathis , Mariana Maccioni , Hong Ji
- Applicant Address: FR Paris
- Assignee: Institut National de la Sante et de la Recherche Medicale (INSERM)
- Current Assignee: Institut National de la Sante et de la Recherche Medicale (INSERM)
- Current Assignee Address: FR Paris
- Agency: Foley & Lardner LLP
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K39/00 ; G01N33/00 ; C12P21/00
Abstract:
The present invention relates to the use of antibodies against glucose-6-phosphate isomerase (GPI) and like protein for diagnosis of arthritis and the use of said protein for treatment of arthritis. It is also aimed at a process for isolating monoclonal antibodies capable of transferring arthritis and antibodies thereof, as well as a method for determining the anti-arthritis potential of a composition.
Public/Granted literature
Information query
