Invention Grant
- Patent Title: Agent for inhibiting proliferation of neural stem cells
- Patent Title (中): 抑制神经干细胞增殖的药剂
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Application No.: US11704185Application Date: 2007-02-09
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Publication No.: US07662385B2Publication Date: 2010-02-16
- Inventor: Hideyuki Okano , Kazunobu Sawamoto , Masanori Sakaguchi , Jun Hirabayashi
- Applicant: Hideyuki Okano , Kazunobu Sawamoto , Masanori Sakaguchi , Jun Hirabayashi
- Applicant Address: JP Tokyo JP Tokyo
- Assignee: Keio University,Advanced Industrial Science and Technology
- Current Assignee: Keio University,Advanced Industrial Science and Technology
- Current Assignee Address: JP Tokyo JP Tokyo
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, LLP
- Priority: JP2006-034444 20060210
- Main IPC: C12N5/00
- IPC: C12N5/00 ; C12N5/06 ; A61K39/00 ; A61K39/395
Abstract:
The object of the present invention is to provide methods for inhibiting proliferation of neural stem cells, an agent for inhibiting proliferation of neural stem cells, and methods for using the same. According to the method of the present invention, a galectin-1 inhibitor such as anti-galectin-1 antibody and/or an integrin β1 inhibitor such as anti-integrin β1 antibody is administered to a human or a vertebrate other than human for inhibiting proliferation of neural stem cells. This method can be used for treatment of nerve injury and nerve tumors.
Public/Granted literature
- US20070248592A1 Agent for inhibiting proliferation of neural stem cells Public/Granted day:2007-10-25
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