Invention Grant
US07662387B2 Anti-cd70 antibody-drug conjugates and their use for the treatment of cancer and immune disorders
有权
抗cd70抗体 - 药物偶联物及其用于治疗癌症和免疫疾病的用途
- Patent Title: Anti-cd70 antibody-drug conjugates and their use for the treatment of cancer and immune disorders
- Patent Title (中): 抗cd70抗体 - 药物偶联物及其用于治疗癌症和免疫疾病的用途
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Application No.: US10546304Application Date: 2004-02-20
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Publication No.: US07662387B2Publication Date: 2010-02-16
- Inventor: Che-Leung Law , Alan F. Wahl , Nathalie Scholler , Linda A. Pestano
- Applicant: Che-Leung Law , Alan F. Wahl , Nathalie Scholler , Linda A. Pestano
- Applicant Address: US WA Bothell
- Assignee: Seattle Genetics
- Current Assignee: Seattle Genetics
- Current Assignee Address: US WA Bothell
- International Application: PCT/US2004/005247 WO 20040220
- International Announcement: WO2004/073656 WO 20040902
- Main IPC: A61K39/00
- IPC: A61K39/00
Abstract:
Disclosed are anti-CD70 antibodies and derivatives thereof conjugated to cytotoxic, immunosuppressive, or other therapeutic agents, as well as pharmaceutical compositions and kits comprising the antibody- and antibody derivative-drug conjugates. Also disclosed are methods, for the treatment of CD70-expressing cancers and immunological disorders, comprising administering to a subject the disclosed pharmaceutical compositions.
Public/Granted literature
- US20060233794A1 Anti-cd70 antibody-drug conjugates and their use for the treatment of cancer and immune disorders Public/Granted day:2006-10-19
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