Invention Grant
- Patent Title: Human and mammalian stem cell-derived neuron survival factors
- Patent Title (中): 人和哺乳动物干细胞衍生的神经元存活因子
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Application No.: US10833108Application Date: 2004-04-28
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Publication No.: US07662620B2Publication Date: 2010-02-16
- Inventor: Tasuku Honjo , Kei Tashiro , Jun Takahashi , Hiroki Toda
- Applicant: Tasuku Honjo , Kei Tashiro , Jun Takahashi , Hiroki Toda
- Applicant Address: JP Osaka JP Kyoto
- Assignee: ONO Pharmaceutical Co., Ltd.,Tasuku Honjo
- Current Assignee: ONO Pharmaceutical Co., Ltd.,Tasuku Honjo
- Current Assignee Address: JP Osaka JP Kyoto
- Agency: Sughrue Mion, PLLC
- Priority: JP2001-325189 20011023
- Main IPC: C12N5/10
- IPC: C12N5/10 ; C12N15/63 ; C07H21/00
Abstract:
The present invention relates to human, rat and mouse stem cell-derived neuron survival factor polypeptides (SDNSF), a process for producing them, cDNA encoding SDNSF, a vector comprising the cDNA, host cells transformed by the vector, an antibody against SDNSF, pharmaceutical compositions containing SDNSF or the antibody, a method of assaying SDNSF, a reagent for assaying SDNSF, and a screening method using SDNSF. The polypeptides are effective in the survival of nerve cells and neuronal stem cells, therefore, efficacious in treating injury to the central nerve system and cancer.
Public/Granted literature
- US20080145365A1 Human and mammalian stem cell-derived neuron survival factors Public/Granted day:2008-06-19
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