Invention Grant
- Patent Title: Adeno-associated virus materials and methods
- Patent Title (中): 腺相关病毒的材料和方法
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Application No.: US11431199Application Date: 2006-05-09
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Publication No.: US07662627B2Publication Date: 2010-02-16
- Inventor: Philip R. Johnson, Jr.
- Applicant: Philip R. Johnson, Jr.
- Applicant Address: US OH Columbus
- Assignee: Nationwide Children's Hospital, Inc.
- Current Assignee: Nationwide Children's Hospital, Inc.
- Current Assignee Address: US OH Columbus
- Agency: Marshall, Gerstein & Borun LLP
- Main IPC: C12N5/08
- IPC: C12N5/08 ; A61K31/711
Abstract:
The present invention provides adeno-associated virus (AAV) materials and methods which are useful for DNA delivery to cells. More particularly, the invention provides recombinant AAV (rAAV) genomes, methods for packaging rAAV genomes, stable host cell lines producing rAAV and methods for delivering genes of interest to cells utilizing the rAAV. Particularly disclosed are rAAV useful in generating immunity to human immunodeficiency virus-1 and in therapeutic gene delivery for treatment of neurological disorders.
Public/Granted literature
- US20060204519A1 Adeno-associated virus materials and methods Public/Granted day:2006-09-14
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