Invention Grant
- Patent Title: Method of screening for inhibitors of osteopontin
- Patent Title (中): 筛选骨桥蛋白抑制剂的方法
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Application No.: US11472730Application Date: 2006-06-22
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Publication No.: US07662633B2Publication Date: 2010-02-16
- Inventor: Simon Barry , Carmel Horgan , Steven Ludbrook
- Applicant: Simon Barry , Carmel Horgan , Steven Ludbrook
- Applicant Address: US PA Philadelphia
- Assignee: GlaxoSmithKline LLC
- Current Assignee: GlaxoSmithKline LLC
- Current Assignee Address: US PA Philadelphia
- Agent Jason C. Fedon; William T. Han
- Priority: GB0007101.0 20000323; GB0106146.4 20010313
- Main IPC: G01N33/00
- IPC: G01N33/00 ; A61K38/04
Abstract:
Amino acids 136 to 142 and amino acids 162 to 168 of human osteopontin constitute two sites at which osteopontin interacts with α4 integrins. Products capable of disrupting those interactions are useful in therapy, particularly in the treatment of inflammatory diseases.
Public/Granted literature
- US20060292648A1 Method of screening for inhibitors of osteopontin Public/Granted day:2006-12-28
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