Invention Grant
US07662770B2 Low molecular weight protein tyrosine phosphatase (LMW-PTP) as a diagnostic and therapeutic target
失效
低分子量蛋白酪氨酸磷酸酶（LMW-PTP）作为诊断和治疗靶点
- Patent Title: Low molecular weight protein tyrosine phosphatase (LMW-PTP) as a diagnostic and therapeutic target
- Patent Title (中): 低分子量蛋白酪氨酸磷酸酶（LMW-PTP）作为诊断和治疗靶点
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Application No.: US10515358Application Date: 2003-05-22
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Publication No.: US07662770B2Publication Date: 2010-02-16
- Inventor: Michael S. Kinch
- Applicant: Michael S. Kinch
- Applicant Address: US IN West LaFayette
- Assignee: Purdue Research Foundation
- Current Assignee: Purdue Research Foundation
- Current Assignee Address: US IN West LaFayette
- Agency: Mueting Raasch & Gebhardt, P.A.
- International Application: PCT/US03/16269 WO 20030522
- International Announcement: WO03/099313 WO 20031204
- Main IPC: A61K38/00
- IPC: A61K38/00
Abstract:
Low molecular weight protein tyrosine phosphatase (LMW-PTP) is identified as a novel diagnostic and therapeutic target in cancer diagnosis, prognosis and treatment. The invention provides diagnostic and treatment methods useful in connection with cancers expressing LMW-PTP and, optionally, EphA2 receptor. Also provided is a screening method that utilizes changes in the amount and/or activity of LMW-PTP to identify candidate cancer therapeutic agents that effectively target the oncoprotein EphA2.
Public/Granted literature
- US20060093608A1 Low molecular weight protein tyrosine phosphatase (lmw-ptp) as a diagnostic and therapeutic target Public/Granted day:2006-05-04
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