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US07662778B2 Histone deacetylase inhibitor and process for producing the same 失效
组蛋白脱乙酰酶抑制剂及其制备方法

  • Patent Title: Histone deacetylase inhibitor and process for producing the same
  • Patent Title (中): 组蛋白脱乙酰酶抑制剂及其制备方法
  • Application No.: US10561298
    Application Date: 2004-06-18
  • Publication No.: US07662778B2
    Publication Date: 2010-02-16
  • Inventor: Minoru YoshidaNorikazu Nishino
  • Applicant: Minoru YoshidaNorikazu Nishino
  • Applicant Address: JP Wako-shi, Saitama
  • Assignee: Riken
  • Current Assignee: Riken
  • Current Assignee Address: JP Wako-shi, Saitama
  • Agency: Fish & Richardson P.C.
  • Priority: JP2003-177298 20030620
  • International Application: PCT/JP2004/008924 WO 20040618
  • International Announcement: WO2004/113366 WO 20041229
  • Main IPC: A61K38/00
  • IPC: A61K38/00
Histone deacetylase inhibitor and process for producing the same
Abstract:
HDAC inhibitor of the general formula (1) exhibits strong inhibitory activity against various subtype HDACs. The compound is useful as a medicinal agent for the treatment or prevention of HDAC 1, 4 and 6-related diseases. There is further provided a process for producing the compound which is capable of readily synthesizing various types of compounds and is promising in the contribution to the development of HDAC inhibitor having novel properties, etc.
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