Invention Grant
US07662785B2 Selective high affinity polydentate ligands and methods of making such
有权
选择性高亲和力多齿配体及其制备方法
- Patent Title: Selective high affinity polydentate ligands and methods of making such
- Patent Title (中): 选择性高亲和力多齿配体及其制备方法
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Application No.: US11055181Application Date: 2005-02-09
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Publication No.: US07662785B2Publication Date: 2010-02-16
- Inventor: Sally DeNardo , Gerald DeNardo , Rodney Balhorn
- Applicant: Sally DeNardo , Gerald DeNardo , Rodney Balhorn
- Applicant Address: US CA Oakland US CA Livermore
- Assignee: The Regents of California,Lawrence Livermore National Security, LLC
- Current Assignee: The Regents of California,Lawrence Livermore National Security, LLC
- Current Assignee Address: US CA Oakland US CA Livermore
- Agent John H. Lee
- Main IPC: A61K38/08
- IPC: A61K38/08
Abstract:
This invention provides novel polydentate selective high affinity ligands (SHALs) that can be used in a variety of applications in a manner analogous to the use of antibodies. SHALs typically comprise a multiplicity of ligands that each bind different region son the target molecule. The ligands are joined directly or through a linker thereby forming a polydentate moiety that typically binds the target molecule with high selectivity and avidity.
Public/Granted literature
- US20060084115A1 Selective high affinity polydentate ligands and methods of making such Public/Granted day:2006-04-20
Information query
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