Invention Grant
- Patent Title: Triazole compounds that modulate HSP90 activity
- Patent Title (中): 调节HSP90活性的三唑化合物
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Application No.: US11506185Application Date: 2006-08-17
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Publication No.: US07662813B2Publication Date: 2010-02-16
- Inventor: Weiwen Ying , David James , Shijie Zhang , Teresa Przewloka , Elena Kostik , Junghyun Chae , Howard P Ng , Zhenjian Du , James Barsoum , Dinesh Chimmanamada , Chi-Wan Lee , Kevin Foley
- Applicant: Weiwen Ying , David James , Shijie Zhang , Teresa Przewloka , Elena Kostik , Junghyun Chae , Howard P Ng , Zhenjian Du , James Barsoum , Dinesh Chimmanamada , Chi-Wan Lee , Kevin Foley
- Applicant Address: US MA Lexington
- Assignee: Synta Pharmaceuticals Corp.
- Current Assignee: Synta Pharmaceuticals Corp.
- Current Assignee Address: US MA Lexington
- Agency: Foley & Lardner LLP
- Agent Steven G. Davis
- Main IPC: A61K31/4196
- IPC: A61K31/4196 ; A61K31/4025 ; A61K31/4523 ; A61K31/506 ; A61K31/5377 ; A61K31/541 ; C07D249/08 ; C07D207/04 ; C07D401/02 ; C07D403/02 ; C07D413/02
Abstract:
The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.
Public/Granted literature
- US20070155809A1 Triazole compounds that modulate HSP90 activity Public/Granted day:2007-07-05
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