Invention Grant
US07662819B2 Pteridinone derivatives for use as stearoyl CoA desaturase inhibitors
失效
用作硬脂酰CoA去饱和酶抑制剂的蝶啶酮衍生物
- Patent Title: Pteridinone derivatives for use as stearoyl CoA desaturase inhibitors
- Patent Title (中): 用作硬脂酰CoA去饱和酶抑制剂的蝶啶酮衍生物
-
Application No.: US11868407Application Date: 2007-10-05
-
Publication No.: US07662819B2Publication Date: 2010-02-16
- Inventor: Jeffrey Chisholm , Dmitry Koltun , Jeff Zablocki , Eric Parkhill , Andrey Glushkov , Natalya Vasilevich , Timur Zilbershtein , Andrew Cole , Tsung Lin , Ian Henderson
- Applicant: Jeffrey Chisholm , Dmitry Koltun , Jeff Zablocki , Eric Parkhill , Andrey Glushkov , Natalya Vasilevich , Timur Zilbershtein , Andrew Cole , Tsung Lin , Ian Henderson
- Applicant Address: US CA Foster City
- Assignee: Gilead Palo Alto, Inc.
- Current Assignee: Gilead Palo Alto, Inc.
- Current Assignee Address: US CA Foster City
- Agent J. Elin Hartrum
- Main IPC: A61K31/519
- IPC: A61K31/519 ; C07D475/00 ; A61P35/00 ; A61P3/10 ; A61P9/00
Abstract:
The present invention discloses pteridinone derivatives for use as inhibitors of stearoyl-CoA desaturase having the structure of Formula I: The compounds are useful in treating and/or preventing various human diseases, mediated by stearoyl-CoA desaturase (SCD) enzymes, especially diseases related to abnormal lipid levels, cardiovascular disease, diabetes, obesity, metabolic syndrome and the like.
Public/Granted literature
- US20080249100A1 PTERIDINONE DERIVATIVES FOR USE AS STEAROYL CoA DESATURASE INHIBITORS Public/Granted day:2008-10-09
Information query
IPC分类:
