Invention Grant
US07662842B2 Thiazolidinone amides, thiazolidine carboxylic acid amides, and serine amides, including polyamine conjugates thereof, as selective anti-cancer agents
失效
噻唑烷酮酰胺，噻唑烷羧酸酰胺和丝氨酸酰胺，包括其多胺缀合物，作为选择性抗癌剂
- Patent Title: Thiazolidinone amides, thiazolidine carboxylic acid amides, and serine amides, including polyamine conjugates thereof, as selective anti-cancer agents
- Patent Title (中): 噻唑烷酮酰胺，噻唑烷羧酸酰胺和丝氨酸酰胺，包括其多胺缀合物，作为选择性抗癌剂
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Application No.: US11458648Application Date: 2006-07-19
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Publication No.: US07662842B2Publication Date: 2010-02-16
- Inventor: Duane D. Miller , James T. Dalton , Veeresa Gududuru , Eunju Hurh
- Applicant: Duane D. Miller , James T. Dalton , Veeresa Gududuru , Eunju Hurh
- Applicant Address: US OH Columbus US TN Knoxville
- Assignee: Ohio State Univesity Research Foundation,The University of Tennessee Research Foundation
- Current Assignee: Ohio State Univesity Research Foundation,The University of Tennessee Research Foundation
- Current Assignee Address: US OH Columbus US TN Knoxville
- Agency: Nixon Peabody LLP
- Main IPC: A61K31/426
- IPC: A61K31/426 ; A61K31/427 ; C07D417/02
Abstract:
Substituted thiazolidinone carboxylic acid amides and substituted thiazolidine carboxylic acid amides according to formulae (I) and (II) are disclosed where the various substituent groups are as defined in the specification. Methods of making these compounds, pharmaceutical compositions containing the compounds, and their use, particularly for treating or preventing cancer, are also disclosed.
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