Invention Grant
- Patent Title: Antibodies to ZCYTO20 (IL-28A) and ZCYTO22 (IL-28B)
- Patent Title (中): ZCYTO20(IL-28A)和ZCYTO22(IL-28B)
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Application No.: US12201399Application Date: 2008-08-29
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Publication No.: US07662927B2Publication Date: 2010-02-16
- Inventor: Paul O. Sheppard , Brian A. Fox , Kevin M. Klucher , David W. Taft , Wayne Kindsvogel
- Applicant: Paul O. Sheppard , Brian A. Fox , Kevin M. Klucher , David W. Taft , Wayne Kindsvogel
- Applicant Address: US TN Nashville
- Assignee: ZymoGenetics, LLC
- Current Assignee: ZymoGenetics, LLC
- Current Assignee Address: US TN Nashville
- Agent Brian J. Walsh
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C12P21/08

Abstract:
The present invention relates to polynucleotide and polypeptide molecules for zcyto20, zcyto21, zcyto22, zycto24, and zcyto25 proteins which are most closely related to interferon-α at the amino acid sequence level. The receptor for this protein family is a class II cytokine receptor. The present invention includes methods of reducing viral infections and increasing monocyte counts. The present invention also includes antibodies to the zcyto20 polypeptides, and methods of producing the polynucleotides and polypeptides.
Public/Granted literature
- US20090149636A1 CYTOKINE PROTEIN FAMILY Public/Granted day:2009-06-11
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