Invention Grant
US07662933B2 N-terminally chemically modified protein compositions and methods
失效
N-末端化学修饰的蛋白质组合物和方法
- Patent Title: N-terminally chemically modified protein compositions and methods
- Patent Title (中): N-末端化学修饰的蛋白质组合物和方法
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Application No.: US11411321Application Date: 2006-04-26
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Publication No.: US07662933B2Publication Date: 2010-02-16
- Inventor: Olaf B. Kinstler , Nancy Elise Gabriel , Christine E. Farrar , Randolph B. DePrince
- Applicant: Olaf B. Kinstler , Nancy Elise Gabriel , Christine E. Farrar , Randolph B. DePrince
- Applicant Address: US CA Thousand Oaks
- Assignee: Amgen Inc.
- Current Assignee: Amgen Inc.
- Current Assignee Address: US CA Thousand Oaks
- Agency: Marshall, Gerstein & Borun LLP
- Main IPC: C08H1/00
- IPC: C08H1/00 ; C07K14/00 ; C07K17/00 ; C07K1/00 ; C07K16/00
Abstract:
Provided herein are methods and compositions relating to the attachment of water soluble polymers to proteins. Provided are novel methods for N-terminally modifying proteins or analogs thereof, and resultant compositions, including novel N-terminally chemically modified G-CSF compositions and related methods of preparation. Also provided is chemically modified consensus interferon.
Public/Granted literature
- US20060233746A1 N-terminally chemically modified protein compositions and methods Public/Granted day:2006-10-19
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