Invention Grant
- Patent Title: Recognition of oligosaccharide molecular targets by polycationic small molecule inhibitors and treatment of immunological disorders and infectious diseases
- Patent Title (中): 通过聚阳离子小分子抑制剂识别寡糖分子靶标,并处理免疫学疾病和感染性疾病
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Application No.: US11693941Application Date: 2007-03-30
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Publication No.: US07662999B2Publication Date: 2010-02-16
- Inventor: Mark R. Burns , Sunil A. David
- Applicant: Mark R. Burns , Sunil A. David
- Applicant Address: US MD Bethesda US DC Washington
- Assignee: National Institutes of Health (NIH),The United States of America as represented by the Department of Health and Human Services (DHHS),U.S. Government NIH Division of Extramural Inventions and Technology Resources (DEITR)
- Current Assignee: National Institutes of Health (NIH),The United States of America as represented by the Department of Health and Human Services (DHHS),U.S. Government NIH Division of Extramural Inventions and Technology Resources (DEITR)
- Current Assignee Address: US MD Bethesda US DC Washington
- Agency: Connolly Bove Lodge & Hutz LLP
- Main IPC: C07C233/01
- IPC: C07C233/01

Abstract:
Small molecule polycationic agents are used to modulate or interrupt biological processes by binding to oligosaccharide-based biomolecules. Compounds that inhibit nitric oxide, TNFα or other immunomodulators are provided and are useful for treating immunological disease and disease of an infectious disorder.
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