Aspects of a method and system for minimizing effects of transmitter impairments in multiple input multiple output (MIMO) beamforming communication systems are presented. In one aspect of a system for minimizing effects of transmitter impairments, a MIMO transmitter may enable nulling of transmitter-induced noise by adjusting at least a portion of a plurality of signals transmitted based on a transmitter error vector magnitude (EVM). The transmitter may enable transmission of the plurality of signals subsequent to the nulling. In another aspect of a system for minimizing effects of transmitter impairments a MIMO receiver may enable nulling of transmitter-induced noise contained in a plurality of received signals based on a transmitter EVM. Each of the plurality of received signals may include information contained in a plurality of spatial streams. The receiver may enable detecting estimated values for the information contained in the plurality of spatial streams based on the nulling.