A power plug with over temperature and over current protection comprises a housing, a plurality of terminals partially embedded in the housing, and a plurality of power cables. The housing is provided with an over temperature and over current protection unit therein. A live terminal of the power plug is directly and electrically connected with the protection unit by either pressing the live terminal immediately against the protection unit or directly welding the live terminal to the protection unit without any wire therebetween. The power plug provides a more direct and efficient heat transfer from the live terminal of the power plug to the protection unit, thereby response sensitivity of the protection unit can be enhanced.