Invention Grant
- Patent Title: Breast homing peptides and methods of identifying same using aminopeptidase P
- Patent Title (中): 乳腺归巢肽和使用氨肽酶P鉴定其的方法
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Application No.: US10158566Application Date: 2002-05-29
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Publication No.: US07666391B2Publication Date: 2010-02-23
- Inventor: Erkki Ruoslahti , Markus Essler
- Applicant: Erkki Ruoslahti , Markus Essler
- Applicant Address: US CA La Jolla
- Assignee: Burnham Institute for Medical Research
- Current Assignee: Burnham Institute for Medical Research
- Current Assignee Address: US CA La Jolla
- Agency: McDermott Will & Emery LLP
- Main IPC: A61K49/00
- IPC: A61K49/00 ; A01N37/18
Abstract:
The present invention provides a method of directing a moiety to breast vasculature in a subject by administering to the subject a conjugate which contains a moiety linked to a homing molecule that selectively homes to breast vasculature, whereby the moiety is directed to breast vasculature. In one embodiment, the homing molecule is a peptide containing the amino acid sequence PGPEGAG (SEQ ID NO: 1), or a peptidomimetic thereof.
Public/Granted literature
- US20030232762A1 Breast homing peptides and methods of identifying same using aminopeptidase P Public/Granted day:2003-12-18
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