Invention Grant
- Patent Title: Anti-CCR5 antibody
- Patent Title (中): 抗CCR5抗体
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Application No.: US11581945Application Date: 2006-10-16
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Publication No.: US07666419B2Publication Date: 2010-02-23
- Inventor: William C. Olson , Paul J. Maddon , Naoya Tsurushita , Paul R. Hinton , Maximillano Vasquez
- Applicant: William C. Olson , Paul J. Maddon , Naoya Tsurushita , Paul R. Hinton , Maximillano Vasquez
- Applicant Address: US NY Tarrytown US CT Redwood
- Assignee: Progenics Pharmaceuticals Inc.,Facet Biotech Corporation
- Current Assignee: Progenics Pharmaceuticals Inc.,Facet Biotech Corporation
- Current Assignee Address: US NY Tarrytown US CT Redwood
- Agency: Cooper & Dunham LLP
- Agent John P. White
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C12N15/13 ; C07K16/28
Abstract:
The invention is directed an anti-CCR5 antibody which comprises (i) two light chains, each light chain comprising the expression product of a plasmid designated pVK:HuPRO14O-VK (ATCC Deposit Designation PTA-4097), and (ii) two heavy chains, each heavy chain comprising an expression product of either a plasmid designated pVgl:HuPRO140 HG2-VH (ATCC Deposit Designation PTA-4098) or a plasmic designated pVgl:HuPRO140 (mutB+D+I)-VH (ATCC Deposit Designation PTA-4099) or a fragment thereof which binds to CCR5 on the surface of a human cell.
Public/Granted literature
- US20070031408A1 Anti-CCR5 antibody Public/Granted day:2007-02-08
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