Invention Grant
- Patent Title: HIV vaccines based on Env of multiple clades of HIV
- Patent Title (中): 基于Env多个艾滋病毒携带者的艾滋病毒疫苗
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Application No.: US11818113Application Date: 2007-06-13
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Publication No.: US07666427B2Publication Date: 2010-02-23
- Inventor: Gary J. Nabel , Bimal Chakrabarti , Wing-pui Kong , Yue Huang , Zhi-yong Yang
- Applicant: Gary J. Nabel , Bimal Chakrabarti , Wing-pui Kong , Yue Huang , Zengguang Wang, legal representative , Zhi-yong Yang
- Applicant Address: US DC Washington
- Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
- Current Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
- Current Assignee Address: US DC Washington
- Agency: Leydig, Voit & Mayer, Ltd.
- Main IPC: A61K39/00
- IPC: A61K39/00
Abstract:
In one embodiment, the invention provides a multiclade HIV plasmid DNA or viral vector vaccine including components from different clades of Env (optionally Env chimeras) and Gag-Pol-(optionally)Nef from a single clade. The vaccine of the invention may further include V1, V2, V3, or V4 deletions or combinations thereof. In another embodiment, the invention provides multiclade HIV envelope immunogens.
Public/Granted literature
- US20080286306A1 HIV vaccines based on Env of multiple clades of HIV Public/Granted day:2008-11-20
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