Invention Grant
US07666585B2 Construction of chimera PRRSV, compositions and vaccine preparations
有权
嵌合体PRRSV，组合物和疫苗制剂的构建
- Patent Title: Construction of chimera PRRSV, compositions and vaccine preparations
- Patent Title (中): 嵌合体PRRSV，组合物和疫苗制剂的构建
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Application No.: US11763822Application Date: 2007-06-15
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Publication No.: US07666585B2Publication Date: 2010-02-23
- Inventor: Xuexian Zhang , Shi-jun Ma
- Applicant: Xuexian Zhang , Shi-jun Ma
- Applicant Address: US MN St. Paul
- Assignee: ProtaTek International, Inc.
- Current Assignee: ProtaTek International, Inc.
- Current Assignee Address: US MN St. Paul
- Agency: Merchant & Gould P.C.
- Main IPC: C12Q1/70
- IPC: C12Q1/70
Abstract:
Chimeric replicons of North American Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) containing the 5′ sequence of an avirulent strain of PRRSV and a 3′ sequence of a virulent strain of PRRSV are provided. Further provided is a method of producing attenuated PRRSV from the chimeric replicon. Also provided are compositions containing the replicon or attenuated virus. Vaccines and a method of vaccinating pigs against PRRSV are also provided.
Public/Granted literature
- US20080311143A1 CONSTRUCTION OF CHIMERA PRRSV, COMPOSITIONS AND VACCINE PREPARATIONS Public/Granted day:2008-12-18
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