Invention Grant
US07666591B2 Single stranded DNA binding proteins from Archaea and uses therefor
有权
来自古菌的单链DNA结合蛋白，并用于此
- Patent Title: Single stranded DNA binding proteins from Archaea and uses therefor
- Patent Title (中): 来自古菌的单链DNA结合蛋白，并用于此
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Application No.: US11035703Application Date: 2005-01-14
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Publication No.: US07666591B2Publication Date: 2010-02-23
- Inventor: Stephen C. Kowalczykowski , Frédéric Chédin , Erica M. Seitz
- Applicant: Stephen C. Kowalczykowski , Frédéric Chédin , Erica M. Seitz
- Applicant Address: US CA Oakland US DC Washington
- Assignee: The Regents of the University of California,The United States of America as represented by the Department of Health and Human Services
- Current Assignee: The Regents of the University of California,The United States of America as represented by the Department of Health and Human Services
- Current Assignee Address: US CA Oakland US DC Washington
- Agency: Townsend and Townsend and Crew LLP
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12P19/34 ; C07K14/195 ; C07H21/02 ; C07H21/04
Abstract:
The invention provides ssDNA-binding proteins from three species of archaeons, Methanococcus jannaschii, Methanobacter theromoautotrophicum, and Archaeoglobus fulgidus, as well as the ability to identify ssDNA-binding proteins from other archaeons. The proteins help render DNA more accessible to DNA polymerase and are robust reagents for a variety of biotechnical processes, including PCR. The invention further provides nucleic acids encoding such proteins, vectors for transfecting host cells, host cells comprising the vectors, and methods of using the proteins.
Public/Granted literature
- US20050164265A1 Single stranded DNA binding proteins from archaea and uses therefor Public/Granted day:2005-07-28
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