A safety bio-molecular sampling and transport system utilizing a docking connector mechanism includes a elongate enclosure having open ends along with a collection sponge slidably disposed within the enclosure. A sponge moving piston is provided within the enclosure and is engagable with a plunger handle which is configured for removably engaging the piston and enabling manual sliding of the collection sponge between the position inside of the elongate structure and a position exterior another end of the enclosure. A specimen capsule configured for removably docking to the enclosure is provided for receiving specimen and is sealable for safe and laborless transport thereof.