Invention Grant
US07666883B2 Antimalarial Baylis-Hillman adducts and a process for the preparation thereof
失效
抗疟药Baylis-Hillman加合物及其制备方法
- Patent Title: Antimalarial Baylis-Hillman adducts and a process for the preparation thereof
- Patent Title (中): 抗疟药Baylis-Hillman加合物及其制备方法
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Application No.: US11366672Application Date: 2006-03-03
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Publication No.: US07666883B2Publication Date: 2010-02-23
- Inventor: Puli Narender , Banda Gangadasu , Uppalanchi Srinivas , Mettu Ravinder , Sriramoju Bharat Kumar , Chilukuri Ramesh , Vaidya Jayathirtha Rao , Janaswamy Madhusudhan Rao
- Applicant: Puli Narender , Banda Gangadasu , Uppalanchi Srinivas , Mettu Ravinder , Sriramoju Bharat Kumar , Chilukuri Ramesh , Vaidya Jayathirtha Rao , Janaswamy Madhusudhan Rao
- Applicant Address: IN New Delhi
- Assignee: Council of Scientific and Industrial Research
- Current Assignee: Council of Scientific and Industrial Research
- Current Assignee Address: IN New Delhi
- Agency: DLA Piper LLP (US)
- Priority: IN2462/DEL/2005 20050912
- Main IPC: A61K31/44
- IPC: A61K31/44 ; C07D213/84
Abstract:
The present invention is directed towards the synthesis of novel and new chloropyridine skeleton based compounds and these are Bayllis Hillman adducts having a remarkable in vitro anti-malarial activity. These compounds have been found to possess anti-malarial activity against chloroquine sensitive and chloroquine resistant Plasmodium falciparum. The anti-malarial compounds of the present invention inhibit the mature schizonts in vitro.
Public/Granted literature
- US20070117822A1 Novel antimalarial baylis-hillman adducts and a process for the preparation thereof Public/Granted day:2007-05-24
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