Invention Grant
US07666913B2 Method of treating or preventing osteoporosis using isotaxiresinol derived from Taxus yunnanensis
有权
使用衍生自云杉红豆杉的异硫氰菊酯治疗或预防骨质疏松症的方法
- Patent Title: Method of treating or preventing osteoporosis using isotaxiresinol derived from Taxus yunnanensis
- Patent Title (中): 使用衍生自云杉红豆杉的异硫氰菊酯治疗或预防骨质疏松症的方法
-
Application No.: US10570252Application Date: 2005-01-27
-
Publication No.: US07666913B2Publication Date: 2010-02-23
- Inventor: Shigetoshi Kadota , Takahiro Nobukawa
- Applicant: Shigetoshi Kadota , Takahiro Nobukawa
- Applicant Address: JP Sagamihara-shi
- Assignee: Kotosugi Inc.
- Current Assignee: Kotosugi Inc.
- Current Assignee Address: JP Sagamihara-shi
- Agency: Westerman, Hattori, Daniels & Adrian, LLP
- Priority: JP2004-026535 20040203
- International Application: PCT/JP2005/001055 WO 20050127
- International Announcement: WO2005/074905 WO 20050818
- Main IPC: A61K31/05
- IPC: A61K31/05 ; A61P19/10
Abstract:
The object of the present invention is to provide a drug effective in treating or preventing osteoporosis. The present invention discloses a therapeutic or preventive drug for osteoporosis having a compound shown in the formula (1) (wherein R1 is an alkyloxy group with the carbon number of 1 to 4) or a pharmaceutically acceptable salt or ester of said compound in the formula (1) as an effective ingredient. In the compound of the formula (1), a substance in which R1 is CH3O is isotaxiresinol derived from Taxus yunanennsis and showed physiological activities in inhibiting bone resorption and improving bone formation.
Public/Granted literature
- US20090143483A1 Therapeutic or preventive drug for osteoporosis comprising isotaxiresinol derived from taxus yunnanensis Public/Granted day:2009-06-04
Information query
