Invention Grant
US07667011B2 Method for the use of [11C] carbon monoxide in labeling synthesis of 11C-labelled acids by photo-induced free radical carbonylation
失效
使用[11C]一氧化碳通过光诱导的自由基羰基化标记11C标记的酸的合成方法
![Method for the use of [11C] carbon monoxide in labeling synthesis of 11C-labelled acids by photo-induced free radical carbonylation](/docs/US/2010-02-23/US07667011B2/abs.jpg.600x600.jpg)
- Patent Title: Method for the use of [11C] carbon monoxide in labeling synthesis of 11C-labelled acids by photo-induced free radical carbonylation
- Patent Title (中): 使用[11C]一氧化碳通过光诱导的自由基羰基化标记11C标记的酸的合成方法
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Application No.: US11293939Application Date: 2005-12-05
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Publication No.: US07667011B2Publication Date: 2010-02-23
- Inventor: Bengt Langstrom , Oleksiy Itsenko
- Applicant: Bengt Langstrom , Oleksiy Itsenko
- Agent Craig Bohlken
- Main IPC: C07F5/00
- IPC: C07F5/00 ; C07C233/02
![Method for the use of [11C] carbon monoxide in labeling synthesis of 11C-labelled acids by photo-induced free radical carbonylation](/abs-image/US/2010/02/23/US07667011B2/abs.jpg.150x150.jpg)
Abstract:
Methods and reagents for photo-initiated carbonylation with carbon-isotope labeled carbon monoxide using alkyl/aryl iodides with water pretreated by a base are provided. The resultant carbon-isotope labeled acids are useful as radiopharmaceuticals, especially for use in Positron Emission Tomography (PET). Associated kits for PET studies are also provided.
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