Embodiments of the present invention provide a mixed-mode amplifier for amplifying signals in data storage devices such as disk drives. In one embodiments, a circuit for amplifying data signals comprises a magnetoresistive sensor having a bias voltage applied thereto; a signal amplifier which amplifies a signal detected by the magnetoresistive sensor having the bias voltage applied thereto; a feedback control block which is coupled to an output of the signal amplifier and outputs a feedback current used to vary a loop gain of the circuit; a bias setting circuit which outputs a bias setting current; and a transimpedance amplifier which receives the bias setting current from the bias setting block and the feedback current from the feedback control block and generates the bias voltage applied to the magnetoresistive sensor.