Invention Grant
- Patent Title: Patient-specific dosimetry
- Patent Title (中): 患者特异性剂量测定
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Application No.: US11200688Application Date: 2005-08-10
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Publication No.: US07668662B2Publication Date: 2010-02-23
- Inventor: Stewart M. Kroll , Jeffry A. Siegal , Richard L. Wahl , Kenneth R. Zasadny
- Applicant: Stewart M. Kroll , Jeffry A. Siegal , Richard L. Wahl , Kenneth R. Zasadny
- Applicant Address: US MI Ann Arbor US PA Philadelphia
- Assignee: The Regents of the University of Michigan,Smithkline Beecham Corporation
- Current Assignee: The Regents of the University of Michigan,Smithkline Beecham Corporation
- Current Assignee Address: US MI Ann Arbor US PA Philadelphia
- Agency: Howson & Howson LLP
- Agent William T. Han, Esq.
- Main IPC: G06F19/00
- IPC: G06F19/00 ; A61K51/00 ; C12P21/08

Abstract:
A patient-specific optimally effective radiation dose for administration of a radiopharmaceutical to a patient for treatment of a disease may be established by basing the calculation of the appropriate therapeutic dose on factors such as the desired total body dose, the maximum tolerated dose, the typical clearance profile of the radiopharmaceutical, the patient's mass or maximum effective mass, and the patient-specific residence time of the radiopharmaceutical or an analog in the whole body of the patient. The use of the method allows for treatment of a patient with an appropriate dose which is maximally effective against the disease yet minimally toxic. The determination of a patient-specific therapeutic dose may be assisted by the use of a software program set to the particular parameters of the radiopharmaceutical.
Public/Granted literature
- US20050288869A1 Patient-specific dosimetry Public/Granted day:2005-12-29
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