A cassette device for an automatic medicine packaging apparatus includes a cassette main body that contains medicine, a dispensing block that aligns medicine for dispensing according to a prescription and a partitioning member that blocks medicine from discharging from the cassette main body and allows medicine to be discharged only when the partitioning member is controlled to discharge medicine according to the prescription. The partitioning member includes a non-deforming portion and a deforming portion that is connected to the non-deforming portion. The non-deforming portion contacts medicine aligned in the dispensing block. The deforming portion deforms when as external force is applied whereby the non-deforming portion can be displaced.