Invention Grant
US07670603B2 Human DNAX toll-like receptor 4 proteins, related reagents and methods
有权
人类DNAX toll样受体4蛋白，相关试剂和方法
- Patent Title: Human DNAX toll-like receptor 4 proteins, related reagents and methods
- Patent Title (中): 人类DNAX toll样受体4蛋白，相关试剂和方法
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Application No.: US12100088Application Date: 2008-04-09
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Publication No.: US07670603B2Publication Date: 2010-03-02
- Inventor: Gerard T. Hardiman , Fernando L. Rock , J. Fernando Bazan , Robert A. Kastelein , Stephen W. K. Ho , Yong-Jun Liu
- Applicant: Gerard T. Hardiman , Fernando L. Rock , J. Fernando Bazan , Robert A. Kastelein , Stephen W. K. Ho , Yong-Jun Liu
- Applicant Address: US NJ Kenilworth
- Assignee: Schering Corporation
- Current Assignee: Schering Corporation
- Current Assignee Address: US NJ Kenilworth
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C12N15/09 ; C12P21/06 ; C07K14/47
Abstract:
Nucleic acids encoding mammalian Toll-like receptors (TLRs) have been identified in human cells. Recombinantly produced TLRs are used in the preparation of antibodies that are capable of binding to the TLRs. The antibodies are advantageously used in the prevention and treatment of septic shock, inflammatory conditions, and viral infections.
Public/Granted literature
- US20080199477A1 HUMAN RECEPTOR PROTEINS; RELATED REAGENTS AND METHODS Public/Granted day:2008-08-21
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