Invention Grant
- Patent Title: Methods of diagnosing tissue fibrosis
- Patent Title (中): 诊断组织纤维化的方法
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Application No.: US10971195Application Date: 2004-10-22
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Publication No.: US07670764B2Publication Date: 2010-03-02
- Inventor: Esther H. Oh , Catherine M. Smith
- Applicant: Esther H. Oh , Catherine M. Smith
- Applicant Address: US CA San Diego
- Assignee: Prometheus Laboratories Inc.
- Current Assignee: Prometheus Laboratories Inc.
- Current Assignee Address: US CA San Diego
- Agency: Townsend and Townsend and Crew LLP
- Main IPC: C12Q1/04
- IPC: C12Q1/04 ; C12Q1/70 ; A61K39/29

Abstract:
The present invention provides a method of diagnosing the presence or severity of tissue fibrosis in an individual by detecting α2-macroglobulin (α2-MG) in a sample from the individual; detecting hyaluronic acid (HA) in a sample from the individual; detecting tissue inhibitor of metalloproteinases-1 (TIMP-1) in a sample from the individual; and diagnosing the presence or severity of tissue fibrosis in the individual based on the presence or level of α2-MG, HA and TIMP-1.
Public/Granted literature
- US20050186561A1 Methods of diagnosing tissue fibrosis Public/Granted day:2005-08-25
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