Invention Grant
US07670777B2 Method for detecting DNA methylation using labelled S-adenosylmethionine analogs
有权
使用标记的S-腺苷甲硫氨酸类似物检测DNA甲基化的方法
- Patent Title: Method for detecting DNA methylation using labelled S-adenosylmethionine analogs
- Patent Title (中): 使用标记的S-腺苷甲硫氨酸类似物检测DNA甲基化的方法
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Application No.: US11904320Application Date: 2007-09-26
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Publication No.: US07670777B2Publication Date: 2010-03-02
- Inventor: Kurt Berlin , Achim Ribbe
- Applicant: Kurt Berlin , Achim Ribbe
- Applicant Address: DE Berlin DE Hilden
- Assignee: Epigenomics AG,Qiagen GmbH
- Current Assignee: Epigenomics AG,Qiagen GmbH
- Current Assignee Address: DE Berlin DE Hilden
- Agency: Kriegsman & Kriegsman
- Priority: DE10151069 20011005
- Main IPC: C12Q1/68
- IPC: C12Q1/68
Abstract:
The invention relates to a method for detecting the methylation status in DNA samples. According to the invention, a DNA methyl transferase and a labeled S-adenosylmethionine derivative allow a detectable label to be covalently bonded to the DNA, in accordance with the respective methylation status of the DNA sample.
Public/Granted literature
- US20080206760A1 Method for detecting DNA methylation using labelled S-adenosylmethionine analogs Public/Granted day:2008-08-28
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