Invention Grant
US07670779B2 Nucleotide mixture for improved nucleic acid amplification performance
有权
用于提高核酸扩增性能的核苷酸混合物
- Patent Title: Nucleotide mixture for improved nucleic acid amplification performance
- Patent Title (中): 用于提高核酸扩增性能的核苷酸混合物
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Application No.: US12069606Application Date: 2008-02-11
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Publication No.: US07670779B2Publication Date: 2010-03-02
- Inventor: Brian Washburn , Douglas Lovern , Hwa-Tang Thomas Wang , Lawrence Burg
- Applicant: Brian Washburn , Douglas Lovern , Hwa-Tang Thomas Wang , Lawrence Burg
- Applicant Address: US NC Durham
- Assignee: bioMerieux, Inc.
- Current Assignee: bioMerieux, Inc.
- Current Assignee Address: US NC Durham
- Agency: Myers Bigel Sibley & Sajovec
- Agent Elizabeth S. Worley
- Main IPC: C12Q1/68
- IPC: C12Q1/68
Abstract:
The present invention relates to modification of amplification buffer used in amplification reactions. The modifications result in a significant improvement in results of amplification. In particular, the present invention provides methods and buffers for performing an amplification reaction utilizing a buffer comprising nucleotide triphosphates comprising treating the buffer to substitute a portion of the nucleotide triphosphates with nucleotide diphosphates.
Public/Granted literature
- US20080248480A1 Novel nucleotide mixture for improved nucleic acid amplification performance Public/Granted day:2008-10-09
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