Invention Grant
US07670783B2 Screening for neurotoxic amino acid associated with neurological disorders
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筛查与神经系统疾病相关的神经毒性氨基酸
- Patent Title: Screening for neurotoxic amino acid associated with neurological disorders
- Patent Title (中): 筛查与神经系统疾病相关的神经毒性氨基酸
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Application No.: US11760668Application Date: 2007-06-08
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Publication No.: US07670783B2Publication Date: 2010-03-02
- Inventor: Paul A Cox , Sandra Banack , Susan Murch
- Applicant: Paul A Cox , Sandra Banack , Susan Murch
- Applicant Address: US UT Provo
- Assignee: The Institute for Ethnomedicine
- Current Assignee: The Institute for Ethnomedicine
- Current Assignee Address: US UT Provo
- Agency: Pillsbury Winthrop Shaw Pittman LLP
- Main IPC: G01N33/48
- IPC: G01N33/48 ; G01N33/50

Abstract:
Methods for screening for neurological disorders are disclosed. Specifically, methods are disclosed for screening for neurological disorders in a subject by analyzing a tissue sample obtained from the subject for the presence of elevated levels of neurotoxic amino acids or neurotoxic derivatives thereof associated with neurological disorders. In particular, methods are disclosed for diagnosing a neurological disorder in a subject, or predicting the likelihood of developing a neurological disorder in a subject, by determining the levels of β-N-methylamino-L-alanine (BMAA) in a tissue sample obtained from the subject. Methods for screening for environmental factors associated with neurological disorders are disclosed. Methods for inhibiting, treating or preventing neurological disorders are disclosed.
Public/Granted literature
- US20070254315A1 SCREENING FOR NEUROTOXIC AMINO ACID ASSOCIATED WITH NEUROLOGICAL DISORDERS Public/Granted day:2007-11-01
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