Invention Grant
- Patent Title: Confluence regulated adhesion molecules useful in modulating vascular permeability
- Patent Title (中): 汇合调节粘附分子可用于调节血管通透性
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Application No.: US12137898Application Date: 2008-06-12
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Publication No.: US07670826B2Publication Date: 2010-03-02
- Inventor: Beat Albert Imhof , Michel Aurrand-Lions
- Applicant: Beat Albert Imhof , Michel Aurrand-Lions
- Applicant Address: CH Coninsins, Vaud
- Assignee: Merck Serono SA
- Current Assignee: Merck Serono SA
- Current Assignee Address: CH Coninsins, Vaud
- Agency: Saliwanchik, Lloyd & Saliwanchik
- Priority: EP99200746 19990311
- Main IPC: C12N1/20
- IPC: C12N1/20 ; C07H21/04 ; C12P21/06 ; C12N15/87
Abstract:
The invention relates to new polypeptides in isolated form belonging to a subfamily of the human immunoglobulin superfamily, which polypeptide shows at least 70% sequence homology with the amino acid sequence of the murine Confluency Regulated Adhesion Molecules 1 or 2 (CRAM-1 or CRAM-2) as depicted in FIG. 3, upper and second row, respectively, and antibodies thereto as well as their use in treatment of inflammation and tumors.
Public/Granted literature
- US20080274970A1 VASCULAR ADHESION MOLECULES AND MODULATION OF THEIR FUNCTION Public/Granted day:2008-11-06
Information query
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