Invention Grant
- Patent Title: N-(3,4-disubstituted phenyl) salicylamide derivatives
- Patent Title (中): N-(3,4-二取代苯基)水杨酰胺衍生物
-
Application No.: US11765011Application Date: 2007-06-19
-
Publication No.: US07671058B2Publication Date: 2010-03-02
- Inventor: Ryukou Tokuyama , Toshifumi Wakamatsu , Tatsurou Ichige , Susumu Muto , Akiko Itai
- Applicant: Ryukou Tokuyama , Toshifumi Wakamatsu , Tatsurou Ichige , Susumu Muto , Akiko Itai
- Applicant Address: JP Tokyo
- Assignee: Institute of Medicinal Molecular Design, Inc.
- Current Assignee: Institute of Medicinal Molecular Design, Inc.
- Current Assignee Address: JP Tokyo
- Agency: Greenblum & Bernstein, P.L.C.
- Priority: JP2006-171221 20060621
- Main IPC: A01N43/42
- IPC: A01N43/42 ; A61K31/44 ; C07D241/04 ; C07D295/00

Abstract:
A compound represented by the following formula (I) or a salt thereof: wherein R1, R2, R3 and R4 represent hydrogen atom, a halogen atom, cyano group, nitro group, a C1-4 alkyl group, a halogenated C1-4 alkyl group or a C1-4 alkoxy group, R5 represents a halogen atom, cyano group, a C1-4 alkyl group, a halogenated C1-4 alkyl group or a C1-4 alkoxy group, R6 represents a C5-7 cycloalkyl group, a substituted C5-7 cycloalkyl group, a 5 to 7-membered completely saturated heterocyclic group or a substituted 5 to 7-membered completely saturated heterocyclic group, X represents a single bond, oxygen atom, sulfur atom, NR7, —O—CH2— or —N(R8)—CH2—, R7 represents hydrogen atom or a C1-4 alkyl group, or R7 may combine with a substituent of R6 to represent a single bond, methylene group or ethylene group, R8 represents hydrogen atom, a C1-4 alkyl group or a C7-12 aralkyl group, which is useful as an active ingredient of a medicament for prophylactic and/or therapeutic treatment of diseases caused by an activation of STAT6 and/or NF-κB.
Public/Granted literature
- US20080227784A1 N-(3,4-disubstituted phenyl) salicylamide derivatives Public/Granted day:2008-09-18
Information query
IPC分类: