Invention Grant
US07671063B2 2,4 Di (hetero) -arylamino-pyrimidine derivatives as ZAP-70 and/or syk inhibitors
失效
2,4-二（杂） - 芳基氨基 - 嘧啶衍生物，如ZAP-70和/或syk抑制剂
- Patent Title: 2,4 Di (hetero) -arylamino-pyrimidine derivatives as ZAP-70 and/or syk inhibitors
- Patent Title (中): 2,4-二（杂） - 芳基氨基 - 嘧啶衍生物，如ZAP-70和/或syk抑制剂
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Application No.: US11377716Application Date: 2006-03-16
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Publication No.: US07671063B2Publication Date: 2010-03-02
- Inventor: Rolf Baenteli , Marie Claude Bernhard , Peter Buehlmayer , Nigel Graham Cooke , Rudolf Duthaler , Klaus Hinterding , Gebhard Thoma , Maurice Van Eis , Anette Von Matt , Louis Walliser , Gerhard Zenke
- Applicant: Rolf Baenteli , Marie Claude Bernhard , Peter Buehlmayer , Nigel Graham Cooke , Rudolf Duthaler , Klaus Hinterding , Gebhard Thoma , Maurice Van Eis , Anette Von Matt , Louis Walliser , Gerhard Zenke
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent Sophie Binet Cross
- Priority: GB0321710.6 20030916; GB0414440.8 20040628
- Main IPC: C07D405/12
- IPC: C07D405/12 ; C07D239/48 ; C07D413/14 ; A61K31/506
Abstract:
Disclosed are pyrimidine derivatives of formula wherein R0, R1, R3 to R9, and Z have a signification as indicated in claim 1, which have interesting pharmaceutical properties.
Public/Granted literature
- US20060247262A1 2,4 Di (hetero) -arylamino-pyrimidine derivatives as ZAP-70 and/or syk inhibitors Public/Granted day:2006-11-02
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